THE AeTIOLOGY OF SYSTEMIC HYPERTENSION

The aetiology of systemic hypertension.

The aetiology of essential hypertension.

The aetiology and pathogenesis of major systemic vasculitides.

Systemic vasculitis is an inflammatory disorder of blood vessels characterized by a perivascular cellular infiltrate around and fibrinoid necrosis within vessel walls. It may accompany a variety ofdiseases and may dominate clinical and pathological findings in polyarteritis (classical and microscopic), the Churg-Strauss syndrome, Wegener's granulomatosis, HenochSchonlein purpura, giant cell art...

Pulmonary hypertension: a review of the aetiology, pathophysiology and management.

Pulmonary hypertension (PH) is defined as a systolic pulmonary artery pressure (PAP) above 30 mmHg and a mean PAP above 25 mmHg. Pulmonary hypertensive diseases (PHDs) encompass a myriad of conditions that cause pulmonary hypertension (PH), hence the Evian Classification was developed for the categorization of the various causes. Pulmonary hypertensive diseases are complex conditions that are d...

Treatment of systemic hypertension.

Systemic hypertension is a major risk factor for cardiovascular disease and is present in 69% of patients with a first myocardial infarction, in 77% of patients with a first stroke, in 74% of patients with chronic heart failure, and in 60% of patients with peripheral arterial disease. Double-blind, randomized, placebo-controlled trials have found that antihypertensive drug therapy reduces cardi...